Our publications on
sleep and chronobiology

The Trondheim Sleep Group's main focus is to conduct clinical trials where we test interventions that improve sleep and circadian rhythmicity. Our trials are conducted in the general population and clinical populations. We also do research on the genetics, physiology, psychology, and epidemiology of sleep and mental disorders.‍

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Selected publications

Kallestad H., Langsrud K., Simpson M.R., Vestergaard C.L., Vethe D., Kjørstad K., Faaland P., Lydersen S., Morken G., Ulsaker-Janke I., Saksvik S.B., Scott J. (2024) Clinical benefits of modifying the evening light environment in an acute psychiatric unit: A single-centre, two-arm, parallel-group, pragmatic effectiveness randomised controlled trial, PLOS Medicine, 21 (12), art. no. e1004380. DOI: 10.1371/journal.pmed.1004380

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Skjold, S. H., Hagen, K., Wheaton, M. G., Kallestad, H., Hjelle, K. M., Björgvinsson, T., & Hansen, B. (2024). Insomnia as a predictor of treatment outcomes in adolescents receiving concentrated exposure treatment for OCD. BMC Psychiatry, 24, 702. https://doi.org/10.1186/s12888-024-04592-1

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Skoglund, H., Sivertsen, B., Kallestad, H., & Vedaa, Ø. (2024). Digital cognitive behavioral therapy for insomnia for people with comorbid psychological distress: A large scale randomized controlled trial. Sleep medicine, 121, 241–250. https://doi.org/10.1016/j.sleep.2024.06.026

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Ramfjord, L. S., Kahn, N., Langsrud, K., Halvorsen, J. Ø. Ø., Morken, G., Saksvik, S., Engvik, L. S. S., Lydersen, S., & Kallestad, H. (2024). Chronotherapy for patients with a depressive episode treated in a public outpatient mental healthcare clinic in Norway: protocol for a randomised controlled trial. BMJ open, 14(1), e076039. https://doi.org/10.1136/bmjopen-2023-076039

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Smevik, H., Habli, S., Saksvik, S. B., Kliem, E., Evensmoen, H. R., Conde, V., Petroni, A., Asarnow, R. F., Dennis, E. L., Eikenes, L., Kallestad, H., Sand, T., Thompson, P. M., Saksvik-Lehouillier, I., Håberg, A. K., & Olsen, A. (2023). Poorer sleep health is associated with altered brain activation during cognitive control processing in healthy adults. Cerebral cortex (New York, N.Y. : 1991), 33(11), 7100–7119. https://doi.org/10.1093/cercor/bhad024

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Kjørstad, K., Faaland, P. M., Sivertsen, B., Kallestad, H., Langsrud, K., Vethe, D., Vestergaard, C. L., Harris, A., Pallesen, S., Scott, J., & Vedaa, Ø. (2022). Sleep and work functioning in nurses undertaking inpatient shifts in a blue-depleted light environment. BMC nursing, 21(1), 187. https://doi.org/10.1186/s12912-022-00973-4

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Kjørstad, K., Sivertsen, B., Vedaa, Ø., Langsrud, K., Vethe, D., Faaland, P. M., Vestergaard, C. L., Lydersen, S., Smith, O. R. F., Scott, J., & Kallestad, H. (2022). The effects of digital CBT-I on work productivity and activity levels and the mediational role of insomnia symptoms: Data from a randomized controlled trial with 6-month follow-up. Behaviour research and therapy, 153, 104083. https://doi.org/10.1016/j.brat.2022.104083

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Scott, J., Vedaa, Ø., Sivertsen, B., Langsrud, K., & Kallestad, H. (2022). Using network intervention analysis to explore associations between participant expectations of and difficulties with cognitive behavioural therapy for insomnia and clinical outcome: A proof of principle study. Journal of psychiatric research, 148, 73–83. https://doi.org/10.1016/j.jpsychires.2022.01.054

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Saksvik-Lehouillier, I., Langvik, E., Saksvik, S. B., Kallestad, H., Follesø, H. S., Austad, S. B., Dahlberg, J., Ringen, H., Tanum, T., Sørengaard, T. A., Karlsen, H. R., Smedbøl, T., & Olsen, A. (2022). High neuroticism is associated with reduced negative affect following sleep deprivation. Personality and Individual Differences, 185, 111291. https://doi.org/10.1016/j.paid.2021.111291

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Heglum, H. S. A., Drews, H. J., Kallestad, H., Vethe, D., Langsrud, K., Sand, T., & Engstrøm, M. (2022). Contact-free radar recordings of body movement can reflect ultradian dynamics of sleep. Journal of sleep research, 31(6), e13687. https://doi.org/10.1111/jsr.13687

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Bredeli, E., Vestergaard, C. L., Sivertsen, B., Kallestad, H., Øverland, S., Ritterband, L. M., Glozier, N., Pallesen, S., Scott, J., Langsrud, K., & Vedaa, Ø. (2022). Intraindividual variability in sleep among people with insomnia and its relationship with sleep, health and lifestyle factors: an exploratory study. Sleep medicine, 89, 132–140. https://doi.org/10.1016/j.sleep.2021.12.006

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Kallestad, H., Scott, J., Vedaa, Ø., Lydersen, S., Vethe, D., Morken, G., Stiles, T. C., Sivertsen, B., & Langsrud, K. (2021). Mode of delivery of Cognitive Behavioral Therapy for Insomnia: a randomized controlled non-inferiority trial of digital and face-to-face therapy. Sleep, 44(12), zsab185. https://doi.org/10.1093/sleep/zsab185

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Kallestad, H., & Scott, J. (2021). Time to put a spotlight on out-patient chronotherapy for depression. BJPsych open, 7(6), e219. https://doi.org/10.1192/bjo.2021.1056

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Vestergaard, C. L., Vedaa, Ø., Simpson, M. R., Faaland, P., Vethe, D., Kjørstad, K., Langsrud, K., Ritterband, L. M., Sivertsen, B., Stiles, T. C., Scott, J., & Kallestad, H. (2021). The effect of sleep-wake intraindividual variability in digital cognitive behavioral therapy for insomnia: a mediation analysis of a large-scale RCT. Sleep, 44(10), zsab118. https://doi.org/10.1093/sleep/zsab118

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Heglum, H. S. A., Kallestad, H., Vethe, D., Langsrud, K., Sand, T., & Engstrøm, M. (2021). Distinguishing sleep from wake with a radar sensor: a contact-free real-time sleep monitor. Sleep, 44(8), zsab060. https://doi.org/10.1093/sleep/zsab060

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Kallestad, H., Saksvik, S., Vedaa, Ø., Langsrud, K., Morken, G., Lydersen, S., Simpson, M. R., Dørheim, S. K., Holmøy, B., Selvik, S. G., Hagen, K., Stiles, T. C., Harvey, A., Ritterband, L., Sivertsen, B., & Scott, J. (2021). Digital cognitive-behavioural therapy for insomnia compared with digital patient education about insomnia in individuals referred to secondary mental health services in Norway: protocol for a multicentre randomised controlled trial. BMJ open, 11(6), e050661. https://doi.org/10.1136/bmjopen-2021-050661

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Scott, J., Kallestad, H., Vedaa, O., Sivertsen, B., & Etain, B. (2021). Sleep disturbances and first onset of major mental disorders in adolescence and early adulthood: A systematic review and meta-analysis. Sleep medicine reviews, 57, 101429. https://doi.org/10.1016/j.smrv.2021.101429

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Scott, J., Langsrud, K., Goulding, I. R., & Kallestad, H. (2021). Let there be blue-depleted light: In-patient dark therapy, circadian rhythms and length of stay. BJPsych Advances, 27(2), 73–84. https://doi.org/10.1192/bja.2020.47

Filosa, J., Omland, P. M., Langsrud, K., Hagen, K., Engstrøm, M., Drange, O. K., Knutsen, A. J., Brenner, E., Kallestad, H., & Sand, T. (2021). Validation of insomnia questionnaires in the general population: The Nord-Trøndelag Health Study (HUNT). Journal of sleep research, 30(1), e13222. https://doi.org/10.1111/jsr.13222

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Saksvik, S. B., Smevik, H., Stenberg, J., Follestad, T., Vik, A., Håberg, A., Asarnow, R. F., Kallestad, H., Skandsen, T., & Olsen, A. (2021). Poor sleep quality is associated with greater negative consequences for cognitive control function and psychological health after mild traumatic brain injury than after orthopedic injury. Neuropsychology, 10.1037/neu0000751. Advance online publication. https://doi.org/10.1037/neu0000751

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Drews, H. J., Scott, J., Langsrud, K., Vethe, D., & Kallestad, H. (2020). Chronobiologically informed inpatient milieu in psychiatric institutions. The lancet. Psychiatry, 7(12), 1013–1014. https://doi.org/10.1016/S2215-0366(20)30459-4

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Saksvik, S. B., Karaliute, M., Kallestad, H., Follestad, T., Asarnow, R., Vik, A., Håberg, A. K., Skandsen, T., & Olsen, A. (2020). The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue throughout the First Year after Mild Traumatic Brain Injury. Journal of neurotrauma, 37(23), 2528–2541. https://doi.org/10.1089/neu.2019.6898

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Saksvik-Lehouillier, I., Saksvik, S. B., Dahlberg, J., Tanum, T. K., Ringen, H., Karlsen, H. R., Smedbøl, T., Sørengaard, T. A., Stople, M., Kallestad, H., & Olsen, A. (2020). Mild to moderate partial sleep deprivation is associated with increased impulsivity and decreased positive affect in young adults. Sleep, 43(10), zsaa078. https://doi.org/10.1093/sleep/zsaa078

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Vedaa, Ø., Kallestad, H., Scott, J., Smith, O. R. F., Pallesen, S., Morken, G., Langsrud, K., Gehrman, P., Thorndike, F. P., Ritterband, L. M., Harvey, A. G., Stiles, T., & Sivertsen, B. (2020). Effects of digital cognitive behavioural therapy for insomnia on insomnia severity: A large-scale randomised controlled trial. Articles, 2(8), e397-e406. https://doi.org/10.1186/s42482-020-0034-9

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Kjørstad, K., Sivertsen, B., Vedaa, Ø., Langsrud, K., Faaland, P. M., Vethe, D., Vestergaard, C. L., Scott, J., & Kallestad, H. (2021). The Effect of Reducing Insomnia Severity on Work- and Activity-Related Impairment. Behavioral sleep medicine, 19(4), 505–515. https://doi.org/10.1080/15402002.2020.1799792

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Scott, J., Langsrud, K., Vethe, D., Kjørstad, K., Vestergaard, C. L., Faaland, P., Lydersen, S., Vaaler, A., Morken, G., Torgersen, T., & Kallestad, H. (2019). A pragmatic effectiveness randomized controlled trial of the duration of psychiatric hospitalization in a trans-diagnostic sample of patients with acute mental illness admitted to a ward with either blue-depleted evening lighting or normal lighting conditions. Trials, 20(1), 472. https://doi.org/10.1186/s13063-019-3582-2